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Antimalarial drug quality in the most severely malarious parts of Africa - a six country study

BATE, Roger
et al
May 2008

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This article describes research conducted on a range of antimalarial drugs, procured from private pharmacies in urban and peri-urban areas in the major cities of six African countries which were subjected to semi-quantitative thin-layer chromatography (TLC) and dissolution testing to measure active pharmaceutical ingredient content against internationally acceptable standards

East African Network for Monitoring Antimalarial Treatment

February 2006

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The East African Network for Monitoring Antimalarial Treatment (EANMAT) is a local initiative to strengthen the regional information base on parasite chemosensitivity, on which rational treatment policy can be based. The Network was formed in 1997 with three countries: Kenya, Uganda and Tanzania. Rwanda joined in 2000 and Burundi in 2002. The network has high-level commitment and support from the Ministries of Health in the countries involved. EANMAT brings together representatives of the National Malaria Control Programmes (NMCPs) of the member countries, together with other operational and research expertise. This provides a dynamic assessment of current antimalarial treatment, and the data upon which policy change can be based. The website provides a seachable database of malaria treatment efficacy patterns, a map of sentinel sites where this data is gathered, the network's newsletter (including back issues), which comes out three times a year and includes articles about drug efficacy, recent research, and treatment programmes, and a fieldworkers' guide to in vivo anti-malarial drug efficacy testing

The quality of anti-malarials : a study in selected African countries

MAPONGA, Charles
ONDARI, Clive
May 2003

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This was a pilot study to assess the quality of anti-malarials in selected African countries, and to determine whether the quality of these products was related to the level of the distribution chain at which the samples were collected. The data from this study indicate significant problems of substandard anti-malarial products circulating within the drug distribution chains in the African region. It therefore recommends that quality surveillance systems be set up within drug regulatory authorities in the region and that support be given to manufacturers to improve compliance with good manufacturing practices

Changing home treatment of childhood fevers by training shop keepers in rural Kenya

MARSH, V M
et al
May 1999

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Malaria control in Africa relies primarily on early effective treatment for clinical disease, but most early treatments for fever occur through self-medication with shop-bought drugs. Lack of information to community members on over-the-counter drug use has led to widespread ineffective treatment of fevers, increased risks of drug toxicity and accelerating drug resistance. This study examined the feasibility and measured the likely impact of training shop keepers in rural Africa on community drug use. It concludes that this approach is both feasible and likely to have a significant impact

PMI : President's malaria initiative

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This website highlights work in combating malaria in 15 of the worst affected countries in Africa. Some information on malaria treatment is available, primarily through recipient country case studies

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